The PUP Sta. Mesa, Manila is composed of three campuses:

 

A. Mabini

The main campus of the University located in Sta. Mesa, Manila. Most of the colleges can be found here.

 

NDC Compound

Also located in Sta. Mesa, Manila, it is the site of the College of Architecture and Fine Arts, College of Engineering, College of Communication, Institute of Technology, and the PUP MassCom Theater.

 

M.H. Del Pilar

One of three campuses in Sta. Mesa, Manila, which houses the PUP Graduate School, Hasmin Hostel, and College of Tourism, Hospitality and Transportation Management.